LCGC North America-04-01-2016

A chiral ionic liquid, namely 1-ethyl-3-methyl imidazole L-tartrate ([EMIM][L-Tar]), was applied as a new chiral ligand for the enantioseparation of tryptophan, tyrosine, and phenylalanine enantiomers by chiral ligand exchange CE. To validate the unique behavior of [EMIM][L-Tar], the performance of L-tartaric acid and 1-ethyl-3-methyl imidazole L-proline as chiral ligands was investigated to make a comparison with [EMIM][L-Tar]. Then the separation mechanism was further discussed. It was proven that [EMIM][L-Tar] was a good chiral ligand and would have good application prospects in separation science.

The past decade has brought exponential growth in the number of mass spectrometry (MS) ionization techniques based on desorption and ionization (DI) processes. Here, the three key applications for DI are discussed: rapid, in situ screening; direct analysis of extracted samples or of planar chromatography spots; and scanning samples along x and y axes.

LCGC North America
LC Troubleshooting

April 01, 2016

Retention times drop from one injection to the next. A systematic approach to troubleshooting can help to quickly identify the problem source.

The Essentials
LCGC North America

April 01, 2016

A summary of what these techniques can tell us from a qualitative and quantitative perspective

LCGC North America

This installment describes high performance liquid chromatography (HPLC) instruments and related products introduced at Pittcon 2016 held in Atlanta, Georgia, or in the year prior. We highlight innovative features and benefits of new HPLC systems, modules, software, and product extensions.

LCGC North America

Our annual review of new LC columns and accessories introduced at Pittcon and through the previous year.

Featured Interview
LCGC North America

April 01, 2016

Milton Lee discusses his career path, his influences, and what was involved in launching three commercial analytical instruments.

Issue PDF
LCGC North America

April 01, 2016

Click the title above to open the LCGC North America April 2016 regular issue, Vol 34 No 4, in an interactive PDF format.