LCGC North America-12-01-2018

Click the title above to open the LCGC North America December 2018 issue in an interactive PDF format.

Is an ultraviolet (UV) detector signal good for anything if the analyst is using a mass spectrometer?

New strategies for “bottom-up” analysis of therapeutic proteins, using faster enzymes, new buffer systems, and optimal column chemistries, enable analysts to perform these studies much faster and with fewer artifacts.

The fundamental principles of UV detection are explained, in a single page.

The versatile size-exclusion ultrahigh-performance liquid chromatography (SE-UHPLC) platform method described here provides superior separation for bispecific monoclonal antibody formats compared to a previous method.

The sum of ranking differences (SRD) is a useful statistical tool for comparing methods, models, columns, or samples. It is also simple and straightforward.

Lloyd Snyder was one the “founding fathers” of high performance liquid chromatography (HPLC). He was one of the most widely cited chromatographers with many important contributions to the field of separation science.

The 2019 ISCC and GCxGC Symposia, May 12–17, 2019, in Fort Worth, Texas, promise to provide an exciting and relevant venue for discussions of the latest developments in chromatography.