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LCGC North America-12-01-2018
LCGC North America
Vol 36 No 12 LCGC North America December 2018 Regular Issue PDF
December 01, 2018
LCGC 1218 December Issue PDF
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Click the title above to open the LCGC North America December 2018 issue in an interactive PDF format.
Letting the Chromatograph Talk, Part I–Looking for Troubleshooting Clues in Unexpected Places
December 01, 2018
LC Troubleshooting
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Is an ultraviolet (UV) detector signal good for anything if the analyst is using a mass spectrometer?
Drawing A Better Map: The Recent Advances in Protein Digestion and Peptide Mapping
December 01, 2018
Column: Column Watch
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New strategies for “bottom-up” analysis of therapeutic proteins, using faster enzymes, new buffer systems, and optimal column chemistries, enable analysts to perform these studies much faster and with fewer artifacts.
How It Works: UV Detection for HPLC
December 01, 2018
The Essentials
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The fundamental principles of UV detection are explained, in a single page.
Development of a MultiProduct SE-UHPLC Method for the Determination of Size-Variants in Bispecific Antibody Formats
December 01, 2018
Peer-Reviewed Articles
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The versatile size-exclusion ultrahigh-performance liquid chromatography (SE-UHPLC) platform method described here provides superior separation for bispecific monoclonal antibody formats compared to a previous method.
Statistics for Analysts Who Hate Statistics, Part VII: Sum of Ranking Differences (SRD)
December 01, 2018
Peer-Reviewed Articles
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The sum of ranking differences (SRD) is a useful statistical tool for comparing methods, models, columns, or samples. It is also simple and straightforward.
Lloyd R. Snyder (1931-2018)–A Personal Tribute
December 01, 2018
Features
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Lloyd Snyder was one the “founding fathers” of high performance liquid chromatography (HPLC). He was one of the most widely cited chromatographers with many important contributions to the field of separation science.
Deep in the Heart of Texas, Chromatography Advances
December 01, 2018
Features
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The 2019 ISCC and GCxGC Symposia, May 12–17, 2019, in Fort Worth, Texas, promise to provide an exciting and relevant venue for discussions of the latest developments in chromatography.