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For your highly sensitive UHPLC–MS analyses, how can you reduce noise and additional signals to a minimum?
For your highly sensitive UHPLC–MS analyses, how can you reduce noise and additional signals to a minimum? Our new high-end UHPLC–MS solvents raise the standard for low baseline noise and clean mass spectra.
Our new range of advanced UHPLC–MS LiChrosolv® solvents have been developed to exceed all expectations, providing rapid and reliable results in both ESI/APCI positive and negative ionization modes.
Thanks to their lowest level of background noise and ion suppression, this quality ensures the optimum ionization efficiency to enable the highest sensitivity. With these features, use of these solvents can also help to extend column lifetime.
To ensure that you have confidence in your results, we specify the lowest possible limit of polyethylene glycol (PEG) impurities in all our UHPLC–MS solvents.
Our advanced UHPLC–MS LiChrosolv solvents have been designed to meet the highest requirements of UHPLC–MS in research and quality control, including proteomics and metabolomics, as well as environmental, clinical, food, or industrial testing applications.
A new standard for the unlimited application of ultrahigh-pressure chromatography has been set.
Features and Benefits
LiChrosolv methanol for UHPLC–MS shows a flat baseline and by far the lowest impurity profile compared to the competition. Both competitor’s high purity UHPLC–MS products A and B show a baseline drift and significant impurity peaks.
Test 1: UHPLC–MS gradient run with LiChrosolv acetonitrile for UHPLC–MS shows a clear detection and identification of 1 ppb reserpine, 500 ppt propazine, and 4 ppb prednisolone, with very low background interferences.
Test 2: Comparison of LiChrosolv methanol for UHPLC–MS (blue line) with two competitor UHPLC–MS products.
To read the rest of this application please visit SigmaAldrich.com/UHPLC–MS.
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