Analysis of Phenolic Compounds in Water
Chemists from Normal University and Wuhan University (both Wuhan, China) used an improved liquid-liquid-liquid microextraction method in the analysis of four phenolic compounds in water.
Chemists from Normal University and Wuhan University (both Wuhan, China) used an improved liquid-liquid-liquid microextraction method in the analysis of four phenolic compounds in water. They used a vial insert as the acceptor phase container. The small diameter of the bottom of the vial insert caused a larger contact area between the acceptor phase and the vial insert and reportedly enabled increased the stability of the microdrop. Because more acceptor phase could be held in the improved method, the sensitivity was also increased. The researchers chose aqueous ammonia as the acceptor phase and toluene as the organic phase.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
