For this application study, the alkaloid compound berberine was selected to help demonstrate the Kinetex PS C18 HPLC/UHPLC column’s unique multi-modal selectivity and improved chromatographic performance when applied to the analysis of polar basic compounds.
Analyze Charge Variants in Antibody-Based Therapeutics Using Cation Exchange Chromatography
July 18th 2024This application note discusses the latest development on high performance cation exchange bio-separation columns for determining charge variants in protein-based biotherapeutics, as well as the strategy on method development.