Analysis of Weak UV-Absorbing Pharmaceutical Drug Substances Using CE with Condensation Nucleation Light-Scattering Detection

June 1, 2001
Donald S. Risley

Eli Lilly and Company Pharmaceutical Product Research and Development, Lilly Research Laboratories, Indianapolis, Indiana.

Michelle L. Lytle

John A. Koropchak

Wei Guo

Lars-Erik Magnusson

LCGC North America

LCGC North America, LCGC North America-06-01-2001, Volume 19, Issue 6

The authors descibe the use of CE with condensation nucleation light-scattering detection to analyze three pharmaceutical analytes. Because the compounds lack adequate UV chromophores, they require a more sensitive means of detection.