Analysis of Weak UV-Absorbing Pharmaceutical Drug Substances Using CE with Condensation Nucleation Light-Scattering Detection

June 1, 2001
Donald S. Risley

Eli Lilly and Company Pharmaceutical Product Research and Development, Lilly Research Laboratories, Indianapolis, Indiana.

,
Michelle L. Lytle

,
John A. Koropchak

,
Wei Guo

,
Lars-Erik Magnusson

LCGC North America

LCGC North America, LCGC North America-06-01-2001, Volume 19, Issue 6

The authors descibe the use of CE with condensation nucleation light-scattering detection to analyze three pharmaceutical analytes. Because the compounds lack adequate UV chromophores, they require a more sensitive means of detection.