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Analysis of Weak UV-Absorbing Pharmaceutical Drug Substances Using CE with Condensation Nucleation Light-Scattering Detection
June 1, 2001
Donald S. Risley , Michelle L. Lytle , John A. Koropchak , Wei Guo , Lars-Erik Magnusson
Donald S. Risley
Eli Lilly and Company Pharmaceutical Product Research and Development, Lilly Research Laboratories, Indianapolis, Indiana.
Michelle L. Lytle
John A. Koropchak
Wei Guo
Lars-Erik Magnusson
LCGC North America
LCGC North America, LCGC North America-06-01-2001, Volume 19, Issue 6
The authors descibe the use of CE with condensation nucleation light-scattering detection to analyze three pharmaceutical analytes. Because the compounds lack adequate UV chromophores, they require a more sensitive means of detection.