Per- and polyfluoroalkyl substances (PFAS) are a diverse group of over 4000 organic fluorinated compounds, which have been widely used in industry since the 1950s. Due to their widespread presence and potential health risks, accurate PFAS analysis is essential to monitor contamination, ensure regulatory compliance, and protect human health and the environment. In this eBook, we explore our range of chromatography and mass spectrometry (MS) solutions for detecting very low levels of PFAS in matrices such as drinking water, wastewater, ambient air, foodstuffs, and consumer products. Plus, learn through a series of case studies how our LC-MS/MS systems and other analytical instruments (GCMS, CIC, QTOF…) meet and often exceed performance criteria included in EPA and AOAC methods for PFAS analysis – generating accurate results with fast turnaround times that enhance lab productivity.
Sam Whitmarsh explores how retention-time models handle interlaboratory data, novel chemotypes, unusual phases and ionisable compounds, and what labs need to do to build useful in-house models.
Sam Whitmarsh describes a practical workflow for predicting reversed-phase LC retention times using ensemble machine learning and open chromatographic data.
Optimized preparation and data-independent acquisition (DIA) liquid chromatography–mass spectrometry (LC-MS) detect up to 6500 proteins in laboratory-grown duck.
Directive (EU) 2024/3019 makes drug manufacturers financially responsible for removing pharmaceutical residues from wastewater and introduces stricter, standardized monitoring requirements that are set to increase demand for trace-level analytical expertise.