Cannabinoid Isomer Separation Utilizing an Analytical Quality by Design (AQbD)
February 19th 2024Cannabinoid separation can be difficult with the presence of coeluting isomers. This application shows how a combination of LabSolutions MD (Method Development) software and powerful i-PDeA technology can help determine the optimal method for cannabinoid separation and deconvolute remaining co-eluting peaks after optimization.
Analysis of 28 Common PFAS Compounds using a Compact Single Quadrupole LCMS
February 19th 2024This application showcases how a compact, affordable single quad LCMS can be easily integrated into existing laboratories for measurement of PFAS in diverse samples where adherence to regulated methods (e.g., EPA 533, 537.1, and 1633) is not required, or samples where expected concentrations are larger than sub ppb levels.
Using SFC to Improve Separation Workflows for Drug Analysis and Purification
November 20th 2023Today’s SFC systems are widely accepted for analytical and preparative separation of chiral and achiral compounds related to pharmaceutical development. Shimadzu enhances the user experience by delivering a highly effective integration of analytical and prep SFC supported by a unified software platform. Learn how these solutions can be used for rapid screening of multiple analytical conditions, simplified method development, and purification at laboratory scale.
Answers to Common FAQs about SFC
November 20th 2023Whether you're an experienced user of SFC technology or just getting into it, this FAQ guide offers a wealth of knowledge to enhance your efficiency, troubleshoot common issues, and make the most of this dynamic tool. Learn about a wide range of topics, including hardware insights, advantages of SFC, applications, and column screening and matrix effects.
Selecting the Right SFC Column
November 20th 2023SFC can provide solutions for challenging separations beyond traditional normal- and reverse-phase HPLC. But to get the best results, you need to select the right columns. This eBook examines column options for accurately and efficiently separating a variety of pharmaceutical compounds using SFC. Topics include SFC column fundamentals and considerations, selecting SFC columns, and columns for SFC chiral and achiral analysis.
Benefits of Using a Hybrid UHPLC/SFC Switching System
November 20th 2023The Nexera UC UHPLC/SFC switching system combines both UHPLC and SFC analysis modes in a single system, allowing you to easily switch between the two techniques in as few as ten minutes without reconnecting flow lines. So, you get the added resolution of UHPLC and the added selectivity of SFC to quickly develop separations without compromising chromatographic accuracy. Learn about five key benefits.
Quantitative Analysis of Azido Impurities in Five Sartan Drug Substances using Triple Quad LCMS
July 11th 2023The work illustrates a single LCMS method for the analysis of AZBT and AMBBT in five sartan drug substances, with full separation of all sartans and azido impurities achieved in only 8.5 minutes.
Data Integrity Compliance in the Analytical Laboratory
July 11th 2023LabSolutions DB/CS software offers powerful support for ensuring compliance with data integrity requirements for all types of analytical instruments, and can be optimized for a wide range of laboratory sizes and operating styles. Download this file to learn more.
The Future of Mass Spectrometry
August 24th 2022Wednesday August 24, 2022 at 10am ET | 3pm BST | 4pm CEST Join us for this virtual symposium as we explore the future of mass spectrometry (MS) technology. Technical talks from scientists at leading mass spectrometry instrument manufacturers will bring you up to date on important developments, including many announced at the ASMS 2022 event. They will explain and demonstrate the technologies underlying advanced capabilities of mass spectrometry techniques and instruments, addressing how those capabilities can translate into performance improvements such as increased sensitivity, greater robustness, and ease-of-use.
Unlocking the Power of 3-D Absorbance Data
September 3rd 2021This podcast will examine peak deconvolution with photodiode array detectors and how a unique software function can separate peaks that are not resolved on-column, yielding better detection results and minimizing method development and analysis time. The podcast will explore the development of this tool with a leading pharmaceutical company and provide examples of how it can have an impact across a wide range of disciplines in the pharma/biopharma arena, from development to production.
Data Integrity: A Virtual Symposium
February 10th 2021***Live: Day One: Wednesday, February 10, 2021 at 9:30am EST - 4:30pm EST *** Day Two: Thursday, February 11, 2021at 9:30am EST - 4:30pm EST *** Join us for this two-day virtual symposium on data integrity with renowned experts Bob McDowall, Chris Burgess, and Mark Newton. This event is aimed at chromatographers and quality assurance professionals who have a working knowledge of data integrity within a regulated GXP laboratory. ***On demand available after final airing until Feb. 10, 2022***