Shimadzu Corporation | Authors

Articles

N-Glycan Analysis of ACE2 as SARS-CoV-2 Receptor

This article shows that the N-glycans of ACE2, a receptor of SARSCoV-2, and their sialic acid linkage types can be easily evaluated using MALDI-TOF analysis.

The Future of Mass Spectrometry

Wednesday August 24, 2022 at 10am ET | 3pm BST | 4pm CEST Join us for this virtual symposium as we explore the future of mass spectrometry (MS) technology. Technical talks from scientists at leading mass spectrometry instrument manufacturers will bring you up to date on important developments, including many announced at the ASMS 2022 event. They will explain and demonstrate the technologies underlying advanced capabilities of mass spectrometry techniques and instruments, addressing how those capabilities can translate into performance improvements such as increased sensitivity, greater robustness, and ease-of-use.

Achieving Improved Sensitivity and Reliable Analytical Performances in Nucleotides Analysis

This app note introduces the use of the Nexera XS inert UHPLC, which utilizes a metal-free flow path for accurate and reproducible analysis of nucleotides.  

Method Optimization for the Analysis of Monoclonal Antibodies by Size-Exclusion Chromatography

This technical report covers how a column packed with small particle material can be used to optimize an analytical method for monoclonal antibody aggregates. 

Oligonucleotides Analysis by Ion-Exchange Chromatography and Effect of pH Changes in the Mobile Phase on Separation

This app note introduces an analytical method for the separation of oligonucleotides of different length by ion-exchange chromatography using the Nexera XS Inert. 

Analysis of Protein Drugs Aggregation Using Size-Exclusion Chromatography

This app note covers aggregate analysis using a Shimadzu Shim-pack™ BioDiol size-exclusion chromatography column with the Nexera XS inert UHPLC.