BTEX in Water Analyzed by Microdrop Extraction and GC-MS
Analysts from the Department of Analytical Chemistry at the University of Cordoba (Cordoba, Spain) used ionic liquid-based, single-drop microextraction followed by gas chromatography with mass spectrometric detection to analyze benzene, toluene, ethylbenzene, and xylene isomers (BTEX) in water.
Analysts from the Department of Analytical Chemistry at the University of Cordoba (Cordoba, Spain) used ionic liquid-based, single-drop microextraction followed by gas chromatography with mass spectrometric detection to analyze benzene, toluene, ethylbenzene, and xylene isomers (BTEX) in water. The ionic extraction liquid, 1-methyl-3-octyl-imidazolium hexafluorophosphate, has a high affinity for the aromatic analytes but is immiscible with water. Repeatability (RSD) for the method reportedly ranged from 3.0% for o-xylene to 5.2% for toluene.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.
