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Figure 3. Comparison of the production method using a volcano plot. Volcano plots highlight features that differ significantly between groups by plotting the magnitude of change vs. statistical significance, making it easy to spot the most important differences.

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Beyond Conventional GC–MS: Revealing Hidden Food Differences

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Figure 2. Split injection used to measure triplicate test of MTBE, hexane, o-xylene, and 1-methylnaphthalene comparing different solvents (methanol, methylene chloride) and column insertion distances starting with 0.5 mm, 5.0 mm, 10.0 mm, 15 mm, and 20.0 mm. Methanol had the best performance at the 5.0 mm insertion distance and methylene chloride looked slightly better at the 0.5 mm. We would still recommend not going below the 5.0 mm manufacturer recommended insertion distance.

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Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.

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SFC–HRMS: Application to the Detection of Drugs of Abuse in Oral Fluid

A novel SFC–QTOF-MS method accurately detected 10 drugs in oral fluid, matching LC–MS/MS in 83 DUID cases while reducing run time by 42% and organic solvent use by 81%.

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