LCGC UST
|Articles|September 1, 2004

LCGC Europe

  • LCGC Europe-09-01-2004
  • Volume 17
  • Issue 9

The Retention Gap Effect

In response to a reader's question, John Hinshaw examines the effects on retention times and peak shapes when a retention gap is added to a capillary column.

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Figure 2. Split injection used to measure triplicate test of MTBE, hexane, o-xylene, and 1-methylnaphthalene comparing different solvents (methanol, methylene chloride) and column insertion distances starting with 0.5 mm, 5.0 mm, 10.0 mm, 15 mm, and 20.0 mm. Methanol had the best performance at the 5.0 mm insertion distance and methylene chloride looked slightly better at the 0.5 mm. We would still recommend not going below the 5.0 mm manufacturer recommended insertion distance.
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.