Controlling Retention in Liquid Chromatography with New Stationary Phases, Temperature, and Modeling

A morning session on controlling retention in liquid chromatography, to be held in Room 122A and with Sarah Rutan of Virginia Commonwealth University presiding, begins at 8:30 am with Anna Forzano, also of Virginia Commonwealth University, speaking on “C8-Ammonium Multicomponent Stationary Phase Gradients on Silica Particle Columns for Strong Anion Exchange and Reversed Phase Liquid Chromatography.”

At 8:50 am, “Multiplicative On-Column Solute Focusing Using Spatially Dependent Temperature Programming for Capillary HPLC” will be presented by Michael Rerick of the University of Pittsburgh.

“Surface Modification of Superficially Porous Silica Particles for HPLC via Diazotization and ‘Craft Knitting’,” by Luis Colon of the University at Buffalo, SUNY, is scheduled for 9:10 am, followed by Erin Shields of the University of Pittsburgh speaking on “pH Stable Liquid Chromatography Stationary Phases Made Using the Thiol-yne Reaction.”

Yong Guo of Fairleigh Dickinson University’s School of Pharmacy will present “A Closer Look at the Retention of Polar Compounds in Hydrophilic Interaction Chromatography (HILIC)” at 10:05 am, to be followed by “Evaluation of Three Temperature- and Mobile Phase-Dependent Retention Models for Reversed-Phase Liquid Chromatography,” presented by Anthony Horner of the University of Pittsburgh at 10:25 am. Next, chairperson Rutan will speak on “Closed Form Expressions for Retention Time and Peak Width in Gradient Liquid Chromatography Based on Linear Solvent Strength and Neue-Kuss Models” at 10:45 am.   

The session concludes with “Evaluation of Chromatography Fundamentals Applied to Weak Cation Exchange Separation of Proteins Charge Variants,” presented by Shane Bechler of Thermo Fisher Scientific, at 11:05 am.