Waters Xevo TQ-S is designed for the most demanding quantitative UPLC/MS/MS applications. Using direct injection on Xevo TQ-S removes sample preparation and enables a simple, high-throughput analysis of pesticides in drinking water.
Xevo™ TQ-S from Waters® is designed for the most demanding quantitative UPLC®/MS/MS applications. It features a revolutionary new off-axis ion source technology, known as StepWave™, which increases even further the high sensitivity provided by Xevo TQ. This advance in performance allows you to accurately, robustly, and reproducibly measure compounds at much lower concentrations than you ever thought possible. Xevo TQ-S also features ScanWave™ collision cell technology to provide enhanced spectral LC/MS/MS data acquisition capabilities. Unlike conventional tandem quadrupole mass spectrometers, the Xevo TQ-S is designed to provide not only the very best quantitative data, but also superior spectral MS/MS information. Using direct injection on Xevo TQ-S removes sample preparation and enables a simple, high-throughput analysis of pesticides in drinking water. This is possible with ultra-sensitive detection down to ppq or pg/L concentrations to enable real background concentrations in samples to be observed. The RADAR mode of acquisition enables the collection of spectral information on background components in the sample matrix while simultaneously collecting MRM data. This can help identify areas of potential ion suppression, observe untargeted contaminants, and aid in the development of matrix reduction strategies.
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Inside the Laboratory: The Gionfriddo Group at the University at Buffalo
March 28th 2024In this edition of “Inside the Laboratory,” Emanuela Gionfriddo, PhD, an associate professor of chemistry at the University at Buffalo, discusses her group’s current research endeavors, including using solid-phase microextraction (SPME) coupled to liquid chromatography (LC) and gas chromatography (GC) to further understand the chemical relationship between environmental exposure and disease and elucidate micropollutants fate in the environment and biological systems.
Transferring Methods to Compact and Portable HPLC
February 14th 2024The current trend in laboratory equipment design is the miniaturization of laboratory instruments. Smaller-scale HPLC instruments offer benefits that cannot be matched by analytical-scale equipment, especially in the areas of portability, reduced fluid volumes, and reduced operating costs. Yet, the miniaturization of laboratory equipment has brought with it a unique set of challenges, including transferring methods to compact LC. Capillary LC expands the use of LC to applications not currently done using conventional LC in a wide array of application areas, including pharmaceutical, food and beverage, petrochemical, environmental, and oil and gas. Greg Ward, Axcend’s CEO wrote, “Customers want an HPLC system with a small footprint, low flow rates and green chemistry.” Join his podcast where he shares method transfer in these application areas.