Determination of Chloramphenicol in Honey with Automated Solid-Phase Extraction and HPLC–MS/MS Detection

Published on: 
, ,

The Application Notebook

The Application Notebook, The Application Notebook-12-01-2017, Volume 30, Issue 4
Pages: 695

A sensitive determination method with automated solid‑phase extraction (SPE) is presented and the recovery rates are compared with manual extraction. The automated extraction was developed with the SPE robot FREESTYLETM SPE module (LCTech GmbH). According to the European Regulation (EC) No 470/2009, CHROMABOND® HLB was applied for SPE (1). A high performance liquid chromatography tandem mass spectrometry (HPLC–MS/MS) method with the biphenyl phase NUCLEODUR® π2 was used for the subsequent analysis.


Neumann-Neander-Str. 6 – 8, 52355 Düren, Germany

Tel.: +49 24 21 969 0  Fax: +49 24 21 969 199

E-mail:  Website: