Automated sequential tube sampling and chemometrics supplement GC–MS, adding time profiling and fast product-line comparison for real-world insight.
|Articles|March 2, 2005
- The Application Notebook-03-01-2005
- Volume 0
- Issue 0
Determination of Protease Inhibitors Used in the Treatment of HIV
Protease inhibitors are a class of anti-HIV drugs used in combination therapy to block replication of the HIV virus in a person's blood. It is important to monitor the levels of these drugs in the patient since resistance can develop at low levels and at high levels the drug can exhibit toxic effects.
Articles in this issue
over 21 years ago
Analysis of Zeaxanthin by Single Quadrupole LC–MSover 21 years ago
Application NotesRelated to this article
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.
A novel SFC–QTOF-MS method accurately detected 10 drugs in oral fluid, matching LC–MS/MS in 83 DUID cases while reducing run time by 42% and organic solvent use by 81%.