Determination of Three Selected Chlorinated Pesticides at Lowest Concentration Level by Fast GC–MS/MS
Pesticides are widely used to protect agricultural products from mould or insect infestation during growth, storage, and product transport. Intensive use or abuse of pesticides can cause environmental pollution in different areas. Lakes, rivers, and aquifers need to be monitored to protect drinking water. Concentration levels of pesticides down to low fg/μL range must therefore be quantified in organic solvent-based water extracts. Typically, large volume injections (LVI) are used to reach this concentration range.
This week on Chromatography Online, leading experts shared practical insights with LCGC International on sustainable affinity methods, siRNA impurity profiling, nontarget screening, peptide tech transfer, and AI in separation science.
Anneli Kruve reports that toxicity predictions from MS2-derived molecular fingerprints outperform spectral-similarity methods in nontarget screening of food.
In this fourth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor explains why buffers are most often used in Mobile Phase A in high-pressure liquid chromatography of pharmaceuticals.