Developments in Multidimensional LC: An HPLC Interview with Andrea Gargano

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At HPLC 2023, LCGC spoke with Andrea Gargano of the Van 't Hoff Institute for Molecular Science at the University of Amsterdam in The Netherlands. These clips comprise one of several HPLC interviews that were conducted at the conference.

Gargano spoke with us at HPLC 2023 in Dusseldorf, Germany, where he presented and moderated on several panels related to research on multidimensional liquid chromatography (LC).

Gargano is an Assistant Professor in the Analytical Chemistry Group at the Van 't Hoff Institute for Molecular Science at the University of Amsterdam in The Netherlands.

In these interview clips, Gargano answers the following:

  1. Why should analysts use 2D-LC when analyzing protein digests? (00:16–01:21)
  2. What problems have analysts encountered when coupling 2D-LC to HRMS when analyzing complex samples? (01:22–02:08)
  3. Can you describe the benefits of the parallel gradient method you developed for protein digest analysis? (02:09–03:43)
  4. Could this parallel gradient method be useful in other applications? (03:44–04:52)
  5. How will artificial intelligence benefit the chromatography community? (04:53–06:05)
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This interview was one of several conducted at HPLC 2023. You can see our latest conference coverage, including our additional video interviews conducted at HPLC, at the following link: https://www.chromatographyonline.com/conferences/hplc