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Chromatography Simplified: Maximizing the Power of PDA Data via Fully Integrated CDS Spectral Processing Tools Combustion Ion Chromatography: The What, How, Why, & Where How to Do More with Less: All Biopharmaceutical Batch Processes Can Benefit from Multi-Column Chromatography Improved Performance of UHPLC–MS Hyphenated Systems Trends and Developments in Liquid Chromatography

Chromatography Simplified: Maximizing the Power of PDA Data via Fully Integrated CDS Spectral Processing ToolsCombustion Ion Chromatography: The What, How, Why, & WhereHow to Do More with Less: All Biopharmaceutical Batch Processes Can Benefit from Multi-Column ChromatographyImproved Performance of UHPLC–MS Hyphenated SystemsTrends and Developments in Liquid Chromatography

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Disulfide Bond Mapping, Comparing Innovator and Biosimilar mAbs

October 11, 2016

Waters Corporation

LCGC Europe

This application note describes a UPLC-MSE analysis of monoclonal antibody (mAb) disulfide bond. This study demonstrates that UNIFI-a compliance-ready software-is designed to support biopharmaceutical laboratories in performing fast peptide mapping and monitoring of mAb disulfide linkages.