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Novel Oligonucleotide Sample Clean-up and Method OptimizationsIt's Not “Just Analytical but With Bigger Columns”— Purification Insourcing and Technology StrategiesHow to Do More with Less: All Biopharmaceutical Batch Processes Can Benefit from Multi-Column ChromatographyOn Replication in Biopharmaceutical AnalysisTools for Investigating the Expanding Per- and Polyfluoroalkyl Substances Universe

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Disulfide Bond Mapping, Comparing Innovator and Biosimilar mAbs

October 11, 2016

Waters Corporation

LCGC Europe

This application note describes a UPLC-MSE analysis of monoclonal antibody (mAb) disulfide bond. This study demonstrates that UNIFI-a compliance-ready software-is designed to support biopharmaceutical laboratories in performing fast peptide mapping and monitoring of mAb disulfide linkages.