Disulfide Bond Mapping, Comparing Innovator and Biosimilar mAbs

Waters Corporation

LCGC Europe

This application note describes a UPLC-MSE analysis of monoclonal antibody (mAb) disulfide bond. This study demonstrates that UNIFI-a compliance-ready software-is designed to support biopharmaceutical laboratories in performing fast peptide mapping and monitoring of mAb disulfide linkages.