Dynamic Liquid-Phase Extraction of Anti-Inflammatory Drugs in Urine
Researchers at the University of Cordoba (Cordoba, Spain) used dynamic liquid-phase microextraction with an ionic liquid as the acceptor phase to extract six nonsteroidal anti-inflammatory drugs from human urine samples.
Researchers at the University of Cordoba (Cordoba, Spain) used dynamic liquid-phase microextraction with an ionic liquid as the acceptor phase to extract six nonsteroidal anti-inflammatory drugs from human urine samples. The extractant liquid was 1-butyl-3-methylimidazolium hexafluorophosphate. The researchers achieved limits of detection ranging from 38 ng/mL to 70 ng/mL and repeatabilities ranging from 2.1% to 3.8%. The analytical method was optimized with respect to chemical, physical, and hydrodynamic variables. The method was found to be useful for drugs in urine in the concentration range 0.1?10 g/mL.
HPLC 2025 Preview: Functionalized Monoliths as Selective Sample Preparation Materials
May 16th 2025Analyzing trace compounds from complex samples often requires purification and pre-concentration, and online coupling of solid-phase extraction (SPE) with liquid chromatography (LC) helps minimize analysis time and solvent/sample use. Monoliths with large macropores are ideal for this coupling due to their low back pressure and versatility in various formats.
Thermodynamic Insights into Organic Solvent Extraction for Chemical Analysis of Medical Devices
April 16th 2025A new study, published by a researcher from Chemical Characterization Solutions in Minnesota, explored a new approach for sample preparation for the chemical characterization of medical devices.
