EGCG Purification from Green Tea Polyphenol Extract using liquid-liquid chromatography

EGCG, or epigallocatechin gallate, is a high-value green tea polyphenol with strong relevance in nutraceutical, botanical, and natural product research. This application note presents a liquid-liquid chromatography workflow for EGCG purification from green tea polyphenol extract using centrifugal partition chromatography. The note demonstrates how support-free separation can help isolate target polyphenols from complex plant-derived matrices where conventional solid-phase chromatography may face limitations.