Two-dimensional gas chromatography (GCxGC) started out as a specialized technique reserved for the domain of academic researchers. But the technique, and the instrumentation, have evolved significantly in the past decade. Does it make sense to use GC x GC in routine analysis? Frank Dorman weighs in.
Two-dimensional gas chromatography has advanced considerably since its first emergence in the late 1980s and its first applications for the hydrocarbon fingerprinting of crude oils. In a new interview, Frank L. Dorman of Penn State University talks about the evolution of GCxGC and the key advantages and disadvantages of the technique, including why fear of its complexity gets in the way of its broader use.
In a recent study, Nick Snow of Seton Hall University studied the presence of drugs of abuse in various complex matrices to detect trace quantities of drugs of abuse such as salvorinin A. In a new short video, Snow explains why used GCxGC–TOF-MS is a good choice for this type of analysis.
