Investigating the Origins of Metabolism
Scientists at the University of Cambridge (Cambridge, UK) have reconstructed the early conditions of the Earth?s oceans to find that spontaneous chemical reactions could have generated the first biological molecules, before the evolution of organisms or the existence of enzymes.1 The study published in the journal Molecular Systems Biology presents data collected from liquid chromatography?triple quadrupole mass spectrometry (LC–QTOF–MS) suggesting that reactions central to our core metabolism could have spontaneously occurred.
High-Throughput 4D TIMS Method Accelerates Lipidomics Analysis
April 25th 2024Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.
