Investigating Vortex Liquid Chromatography: An HPLC Interview with Wim De Malsche

Ceftazidime and avibactam are two anti-infective drugs that can prove difficult to analyze in serum. Determining them can assist in therapeutic drug monitoring or pharmacokinetic studies.

LCGC International spoke to Adrián de la Fuente and Silvia Valverde Bastardo from the University of Valladolid, Spain, about the development of a miniaturized headspace solid-phase microextraction gas chromatography–quadrupole time-of-flight mass spectrometry (HS-SPME-GC–QTOF-MS) method for the analysis of biogenic volatile organic compounds (BVOCs) emitted by native Spanish trees.

Flavonoids are widely used metabolites that carry out various functions in different industries, such as food and cosmetics. Detecting, separating, and quantifying them in fruit species can be a complicated process.

Highly reactive aldehydes can pose significant health concerns in polluted environments. HPLC was used in this study to simultaneously analyze carbonyl compounds hydrazones.

Here is some of the most popular content posted on LCGC International this week.

A recent roundtable discussion featuring Aloka Srinivasan of Raaha, Mayank Bhanti of the United States Pharmacopeia (USP), and Amber Burch of Purisys discussed the challenges surrounding nitrosamine analysis in pharmaceuticals.