Lab Water Hints and Tips for the Chromatography Lab

Researchers built a reliable breath collection and analysis method using thermo-desorption gas chromatography-mass spectrometry (TD-GC–MS) that can produce a comprehensive list of known volatile organic compounds (VOCs) in the breath of a heterogeneous human population.

Université d’Orleans and Chromisa Scientific scientists recently created a two-dimensional supercritical fluid chromatography (SFC) system with multiple heart-cutting (MHC) modes.

In high-performance liquid chromatography (HPLC), it is common for bases and unreacted ionized silanols on silica-based columns to cause irreproducible retention, broad peaks, and peak tailing when working with basic analytes. David S. Bell, Lead Consultant at ASKkPrime LLC offers innovative HPLC strategies that can help mitigate such issues.

A study investigating the changes in volatile compounds in chicken flesh after being chilled in storage for 7 d and subsequently boiled at various pHs assessed the compounds qualitatively and quantitatively via headspace gas chromatography–mass spectrometry (GC–MS) analysis.

Petroleum contamination from leaking underground storage tanks, for example, is a significant concern for both the environment and human health. Thorough characterization of the contamination is required to form appropriate risk assessments and remediation strategies, but until now, the determination of total petroleum hydrocarbons (TPHs) in soil has typically involved a convoluted and labour-intensive process. In this article, the analysis of TPH in environmental media is simplified using flow-modulated GC×GC–FID with quantitation based on pre-defined compound groupings. This approach overcomes the drawbacks of conventional solvent fractionation approaches, by eliminating the need for sample fractionation and automating data processing workflows.