The authors investigated the two most popular types of interfaces for benchtop LC–MS systems – the particle interface and the atmospheric-pressure ionization interface – to learn how the information obtained separately from the two can be complementary.
LCGC 18(2), 162–178 (2000).Chemical Fingerprinting of Urban Runoff Using a Combined Iterative DDA and DIA Workflow
June 19th 2025An innovative workflow that combines iterative data-dependent acquisition (DDA) and data-independent acquisition (DIA) to enhance the identification of unknown pollutants in urban runoff is presented.
Emerging Trends and Challenges in Detecting Residues and Contaminants in Food in the Exposome Era
June 18th 2025This article describes the analytical challenges of chemical exposomics in food safety. The need for high-throughput, multi-platform approaches—such as LC–HRMS and GC–HRMS with IMS—to capture the full spectrum of potential contaminants in our food supply is emphasized.
New Research Explores Role of Nucleotide Hydrophobicity in Oligonucleotide Separation
June 18th 2025Researchers from Waters and Biospring studied the contribution of nucleotide type and modifications on the retention and resolution of 22–24 nt long oligonucleotides in different chromatographic methods.