|Articles|March 21, 2022

LC-MS Analysis of Various Non-modified and Modified Oligonucleic Acids using the Shodex™ HILICpak™ VN-50 2D

Phosphorothioated oligonucleotides were successfully separated with the VN-50 2D without ion-pairing and a simple acetonitrile/ammonium formate gradient.

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