Paper spray-mass spectrometry vs. liquid chromtography-tandem mass spectrometry (LC-MS/MS): Can rapid screening rival the gold standard in ER drug testing?
|Articles|March 7, 2013
- The Column-03-07-2013
- Volume 0
- Issue 4
Market Profile: Market Profile: Solid-Phase Extraction
Solid-phase extraction (SPE) has been commercially available for nearly 25 years and is still finding new applications. Growth of this technique appears to be largely a function of the vendors' capability to provide specific application support, especially in clinical sciences, pharmaceuticals, toxicology, pesticides and residues analysis.
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Solid-phase extraction (SPE) has been commercially available for nearly 25 years and is still finding new applications. Growth of this technique appears to be largely a function of the vendors’ capability to provide specific application support, especially in clinical sciences, pharmaceuticals, toxicology, pesticides and residues analysis.
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Liquid chromatography-tandem mass spectrometry (LC-MS/MS) finds high fentanyl levels do not predict toxicity in tolerant users.
Gas chromatography-ion mobility spectrometry (GC-IMS) identifies odor markers that flag early mold growth in cigar tobacco.
Lorna Nisbet from the Leverhulme Research Centre for Forensic Science, discusses a GC–MS. technique developed to detect anabolic-androgenic steroids in e-cigarettes seized from Scottish prisons.
Kinjal Bhatt and Ina Varfaj trace their pull toward analytical science to a saturated chromatography peak and the moment their first chiral peaks separated.
Gérard Hopfgartner explains why pairing SFC with dopant-assisted APPI can match, or even beat, electrospray sensitivity, even at microflow LC rates.
Emma Macturk from LECO Corporation explains which forensic applications benefit from GC×GC’s greater peak capacity, and when the additional separation power may only provide limited benefits.
Koji Yamaguchi of the International University of Health and Welfare (Narita, Japan) discusses a novel derivatized liquid chromatography-tandem mass spectrometry (LC-MS/MS) method plus propofol glucuronide (PRG) marker which improves forensic propofol detection.
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