Massively Parallel Phase Analysis Light Scattering Enables Reliable Mobility Measurements of Proteins, Nanoparticles and Colloids

The Column

The Column, The Column-11-07-2012, Volume 8, Issue 20
Pages: 16–21

Traditionally, measuring the mobility of proteins and nanoparticles has been a challenging task. An effective measurement method traditionally used is phase analysis light scattering (PALS), a technique based on interfering laser light scattered from a sample solution. However, it has been associated with two important shortcomings. Massively Parallel Phase Analysis Light Scattering (MP-PALS) has emerged as a viable alternative to the conventional PALS method.

Traditionally, measuring the mobility of proteins and nanoparticles has been a challenging task. An effective measurement method traditionally used is phase analysis light scattering (PALS), a technique based on interfering laser light scattered from a sample solution. However, it has been associated with two important shortcomings. Massively Parallel Phase Analysis Light Scattering (MP–PALS) has emerged as a viable alternative to the conventional PALS method.

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