Molecularly Imprinted Polymer SPE of Quinolones

Researchers from Hebei University and Baoding University (both in Baoding, China) used water-compatible molecularly imprinted polymers as a sorbent for solid-phase extraction (SPE) of nine quinolones from urine samples. They used UV and IR spectroscopy and proton nuclear magnetic resonance spectroscopy to investigate the sorbent’s molecular recognition mechanisms. The sorbent was able to extract the analytes selectively and simultaneously eliminate matrix interferences. Detection limits for the method reportedly were in the 0.036–0.10 µg/mL range.