LCGC Europe
The authors provide suggestions for the sample pretreatment and analysis of aerosol particles including the use of on-line SFE–LC–GC–MS, GCXGC and LC–MS. Although each technique has its merits, the novel multidimensional systems and those integrating sample pretreatment with the final analysis proved to be valuable tools in aerosol analysis.
The Reality Behind Column Insertion Distance
September 10th 2024Column insertion distance is critical to good chromatography. What happens if the column is installed too low in the injection port? Is insertion distance more important when performing split injection or splitless injection? Does the position of the column in the injection port impact reproducibility?
Modern HPLC Strategies: Improving Retention and Peak Shape for Basic Analytes
August 16th 2024In high-performance liquid chromatography (HPLC), it is common for bases and unreacted ionized silanols on silica-based columns to cause irreproducible retention, broad peaks, and peak tailing when working with basic analytes. David S. Bell, Lead Consultant at ASKkPrime LLC offers innovative HPLC strategies that can help mitigate such issues.