Overcoming Compound Volatility with Sub-ambient ELSD

Polymer Laboratories, now a part of Varian, Inc. has published an application note on Overcoming Compound Volatility with Sub-ambient ELSD. Sub-ambient evaporative light scattering detection is valuable in the analysis of semi-volatile compounds. The Varian 385-LC has been specifically developed to operate at sub-ambient evaporation temperatures, using a Peltier cooled evaporation tube. This application note shows that sub-ambient ELSD at 20 ?C, as delivered by the new Varian 385-LC, increases the accuracy of measurement by minimizing compound volatility effects.