News|Articles|July 16, 2026

Rapid proteomics sample preparation with on-column digestion

Author(s)Tecan

This application note demonstrates an automated workflow for the analysis of trypsin-digested bovine serum albumin (BSA), combining on-column digestion and peptide clean-up using solid phase extraction (SPE) within a single column. Using automated positive pressure processing, the workflow streamlines sample preparation, reduces hands-on time and delivers consistent, reproducible peptide recovery for downstream analysis.


Related to this article

Best of the Week:  SFC Takes the Spotlight
This week's top stories on the Chromatography Online website spotlight LCGC International's new SFC-focused interview series charting the technique's rise alongside LC and GC, complemented by a practical GC data-reporting refresher and a study using chromatography to detect trace pesticides in tap water.