This application note demonstrates an automated workflow for the analysis of trypsin-digested bovine serum albumin (BSA), combining on-column digestion and peptide clean-up using solid phase extraction (SPE) within a single column. Using automated positive pressure processing, the workflow streamlines sample preparation, reduces hands-on time and delivers consistent, reproducible peptide recovery for downstream analysis.
Kirstine Nielsen of Aarhus University (Denmark) discusses how targeted metabolomics ratios helped build a robust bloodstain time-since-deposition tool.
Gérard Hopfgartner explains how atmospheric pressure photoionization can generate radical cations in LC–MS, unlocking EI-style spectra and NIST's spectral library.
LCGC International spoke to Akina Nara of Japan’s Tohoku Medical and Pharmaceutical University about a new study which links a blood compound to how long a body has been dead.
A method coupling gas chromatography-tandem mass spectrometry (GC-MS/MS) and multiple reaction monitoring (MRM) tracks lipid markers of decomposition in commingled remains.
This week's top stories on the Chromatography Online website spotlight LCGC International's new SFC-focused interview series charting the technique's rise alongside LC and GC, complemented by a practical GC data-reporting refresher and a study using chromatography to detect trace pesticides in tap water.