Researchers Discover Intravenous Immune Globulin Improves Quality of Life in Patients With Chronic Inflammatory Demyelinating Polyneuropathy
Researcher Ingemar S. J. Merkies, MD, (Rotterdam, The Netherlands) and colleagues discovered that patients with chronic inflammatory demyelinating polyneuropathy (CIDP) benefit from treatment with immune globulin intravenous 10% caprylate/chromatography purified (IGIV-C).
Researcher Ingemar S. J. Merkies, MD, (Rotterdam, The Netherlands) and colleagues discovered that patients with chronic inflammatory demyelinating polyneuropathy (CIDP) benefit from treatment with immune globulin intravenous 10% caprylate/chromatography purified (IGIV-C). The study consisted of 117 patients, aged 18 years or older, with CIDP and progressive or relapsing motor and sensory dysfunction of at least 1 limb and clinical disability ranging from 2 to 9 on the Inflammatory Neuropathy Cause and Treatment (INCAT) disability scale. Results of the study, presented on September 22 at the American Neurological Association 133rd Annual Meeting , show that patients treated with IGIV-C had a greater improvement on the physical component score of the Short Form-36 Quality of Life Scale (SF-36) compared with those treated with placebo (P = .020).
Paraben Exposure and Childhood Obesity Risk in Preschoolers: UPLC-MS/MS Insights from Recent Study
July 14th 2025Researchers speculating that exposure to paraben in early childhood is associated with changes in satiety hormones performed analysis of urinary methyl, ethyl, propyl, and butylparaben (MeP, EtP, PrP, BuP) levels in 4–6-year-old children, using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).
GC-MS Sheds Light on Chemical Communication Between Desert Locusts
July 9th 2025A multinational research team used behavioral assays and gas chromatography-mass spectrometry (GC-MS) to examine short- and long-term interactions between juvenile and adult desert locusts to test their hypothesis that cross-stage interactions influence juvenile cohesion and physiological traits.
