Separation Science —The State of The Art in Life Science Analysis: A Virtual Symposium

Join leading experts in separation science for a free two-day virtual symposium exploring the latest analytical innovations transforming large- and small-molecule analysis — from next-generation mRNA characterization to advanced small-molecule method optimization.

Register Free: https://www.chromatographyonline.com/lcgc_w/state-of-art-2025

Event Overview:

Separation Science —The State of The Art in Life Science Analysis: A Virtual Symposium
Separation scientists play a pivotal role in the development of innovative therapeutics that benefit human health and society. In this special two-day symposium organized by LCGC International in collaboration with the Chromatographic Society (ChromSoc), leading practitioners in the field will discuss the latest cutting-edge trends and technologies used for both small-molecule and large-molecule analysis. The first day will focus on large molecule analysis, and the second day will focus on small molecule analysis, and will be moderated by Alasdair Matheson, Executive Editor of LCGC International. The second session on both days will contain presentations from leading chromatography companies demonstrating how their technologies can benefit separation scientists in practice.

Attendance is free. Don’t miss this opportunity to learn from leading separation scientists from the world of life science analysis.

Top Reasons to Attend:

Are you a separation scientist working in pharmaceutical or biopharmaceutical analysis? Take your theoretical and practical expertise to the next level with insights into the latest analytical breakthroughs, including:

• Next-Gen mRNA Characterization: Discover modern separation techniques designed to tackle the complexity of mRNA molecules.
• Precision Analysis of RNA Therapeutics: Learn how LC–HR–MS is revolutionizing the detection and quantification of small RNA-based drugs.
• Smarter Small Molecule Strategies: See how mechanistic modeling and surface characterization drive smarter, faster method development and optimization.
• Tracking Plastic Additives in Medical Devices: Learn about the use of online SFE–SFC–MS methods to monitor and analyze leachables and extractables from plastic components.
• Advanced PS80 Quantification: Get up to speed with state-of-the-art approaches to measuring polysorbate 80 content in complex pharmaceutical formulations.
• Oligonucleotides and Sustainability: Learn about the latest developments in green chemistry for oligo analysis.
• Antibody-drug Conjugates: Advantages and Disadvantages of Separation Science-based Methods.

Stay at the forefront of analytical innovation and make confident, informed decisions in your laboratory with these powerful tools and methodologies.


Who Should Attend:

• Separation scientists who specialize in pharmaceutical and biopharmaceutical analysis.

Event Agenda
Wednesday, December 3rd, 2025
The State of Art in Biopharmaceutical Analysis

Morning Session, 9:15am EST - 11:30am EST 

  9:15 am EST Introduction
Alasdair Matheson, Executive Editor, LCGC International

9:30 am EST Advancing High-Throughput Analytical Workflow of mRNA and Lipid Nanoparticle (LNP) Development
Wan-Chih Su, Principal Scientist, Synthetic: Molecule Analytical Chemistry, Genentech Inc.

9:50 am EST Innovative Chromatographic Strategies to Characterize mRNA-based Medicines 
Davy Guillarme, Senior lecturer, University of Geneva, Switzerland

10:10 am EST Sustainability Considerations in the Development Of Oligonucleotide Chromatographic Methods
Paul Ferguson, Principal Scientist, Analytical Science, Astra Zeneca, Macclesfield, United Kingdom

10:30 am EST Characterization of small RNA-based therapeutics by LC-HRMS: technological considerations and analytical challenges
Silvia Millán-Martín, Senior Research Scientist, Characterisation and Comparability Lab (CCL) at the National Institute for Bioprocessing Research and Training (NIBRT), Dublin, Ireland

10:50 am EST Antibody-drug Conjugates: Advantages and Disadvantages of Separation Science-based Methods.
Dr. Marcello Locatelli, Associate Professor, University "G. d'Annunzio" of Chieti-Pescara; Department of Science; Chieti, Italy.

11:10 am EST Live Q&A Session

11:30 am EST Session end/lunch break


Afternoon Session, 11:45am EST - 12:25pm EST 
Experts from leading chromatography companies describe how new chromatography technologies can achieve results in life science analysis in practice.


11:45am EST Employing Multidimensional Design Space Modeling Across Frequent Chromatographic Challenges—Use Cases from Recently Published Results
Arnold Zöldhegyi, Researcher & Application Specialist, Molnár-Institute for Applied Chromatography


12:05pm EST From R&D Discovery to Decision: The Transformative Power of Scientific AI and Transparent Data
Yasmin Emamgholi, Global Product Manager, LabVantage Inc.
Steffen Schlimmer, Global VP Strategic Business Partnerships, LabVantage Inc.

12:25pm EST Unlocking Peak Performance: Enhancing Peptide and Oligonucleotide Analysis with Ultra Inert HPLC Technology
Anne Blackwell, Product Manager Bio LC Columns, Agilent Technologies


12:45pm EST Session End  

Thursday, December 4th, 2025
The State of Art in Pharmaceutical Analysis

Morning Session, 9:15am EST - 11:00am EST 

9:15 am EST Introduction
Alasdair Matheson, Executive Editor, LCGC International

9:30 am EST Fundamental and Practical Aspects of Small Molecule Separations: From Mechanistic Insights to Quality Control Fundamental and Practical Aspects of Small Molecule Separations: From Mechanistic Insights to Quality Control
Professor Torgny Fornstedt, Professor of Analytical Chemistry, Karlstad University, Sweden

9:50 am EST Investigating Plastic Additives and Their Migrations from Medical Devices with Online SFE–SFC–MS Methods
Caroline West (co-authors: Benjamin Caux, Clément De Saint Jores, Ramy Abou-Naccoul, Shinnosuke Horie, Toshiyuki Yamishita, Takeshi Bamba), Full Professor in Analytical Chemistry, University of Orleans, France
 
10:10 am EST Analysis of PS80 Content in Pharmaceutical Formulations
Daniel Steyer, Principal Scientist, GSK, USA

10:30 am EST Question-and-answer session with all the speakers in the session

11:00 am EST Session end/lunch break
                           
                          Afternoon Session, 11:15am EST - 11:35pm EST
Experts from leading chromatography companies describe how new chromatography technologies can achieve results in life science analysis in practice.                           
    
11:15am EST Analytical Quality by Design Approaches for GLP-1 RA Impurity Profiling
  Pawel Bigos, Senior Scientist, Waters Corporation                
                
Featured Speakers:

Wan-Chih Su
Principal Scientist
Synthetic: Molecule Analytical Chemistry, Genentech Inc

Silvia Millán-Martín
Senior Research Scientist
Characterisation and Comparability Lab (CCL) at the National Institute for Bioprocessing Research and Training (NIBRT), Dublin, Ireland

Torgny Fornstedt
Professor of Analytical Chemistry
Karlstad University, Sweden

Caroline West
Full Professor in Analytical Chemistry
University of Orleans, France

Arnold Zöldhegyi
Researcher & Application Specialist
Molnár-Institute for Applied Chromatography

Yasmin Emamgholi
Global Product Manager
LabVantage Inc.

Steffen Schlimmer
Global VP Strategic Business Partnerships
LabVantage Inc.

Pawel Bigos
Senior Scientist
Waters Corporation

Paul Ferguson
Principal Scientist
Analytical Science, Astra Zeneca, Macclesfield, United Kingdom

Dr. Marcello Locatelli
Associate Professor
University

Davy Guillarme
Senior lecturer
University of Geneva, Switzerland

Anne Blackwell
Product Manager Bio LC Columns
Agilent Technologies

Register Free: https://www.chromatographyonline.com/lcgc_w/state-of-art-2025