Vol 21 No 1 LCGC Asia Pacific February/March 2018 Regular Issue PDF

Researchers from the University of Murica (Murica, Spain), the Carlos III Health Institute (Madrid, Spain), and the University of Siena (Siena, Italy) evaluated the concentration of polychlorinated biphenyls (PCBs) in chinstrap penguins and krill from Deception Island (South Shetland Islands, Antarctica) to provide additional data of the PCB presence in Antarctica. To this end, 34 samples of different tissues corresponding to four adult specimens and six chicks were analyzed with gas chromatography.

In episode #37 of Analytically Speaking, podcast host Dr. Jerry Workman speaks with Dr. Austin Daniels, application scientist for Yokogawa Fluid Imaging Technologies, about flow imaging microscopy (FIM), a new technology for sub-visible particle characterization in biologics.

Discover Restek's new PFAS certified reference materials, designed to simplify lab analysis and enhance accuracy for water and food testing.

A new cancer detection test to analyze volatile organic compounds through urine analysis, was granted the Breakthrough Device Designation status by the U.S. FDA. The system, which is built on gas chromatography–mass spectrometry (GC–MS) and proprietary AI, generates real-time cancer risk scores.

John Yates’ lab is using MOBILion’s Parallel Accumulation Mobility Aligned Fragmentation (PAMAF) technology to enhance the DeGlyPHER workflow, which enables detailed, site-specific analysis of N-glycosylation in viral spike proteins such as SARS-CoV-2. This method combines sequential deglycosylation with high-sensitivity LC-MS to quantify glycan occupancy and processing, offering insights into the relationship between glycosylation and immune response. DeGlyPHER has been applied to over 200 vaccine candidates, including those for HIV, influenza, and Ebola, advancing understanding of glycoprotein-based immunogen design. This executive summary explains how DeGlyPHER is transforming vaccine development in real time, driving progress toward more effective and consistent immunization strategies, and delivering a more sensitive and high-throughput approach compared to traditional glycoproteomic methods.