This Wednesday morning session begins at 9:00 am with Leonard Sidisky, Jamie Desorcle, Greg Baney, and Kathy Kiefer of MilliporeSigma presenting “Latest Developments in Ionic Liquid Stationary Phase Technology.”
This Wednesday morning session taking place in Exhibit Hall #4 begins at 9:00 am with Leonard Sidisky, Jamie Desorcle, Greg Baney, and Kathy Kiefer of MilliporeSigma presenting “Latest Developments in Ionic Liquid Stationary Phase Technology.” The presentation will compare and contrast the selectivity of the ionic liquids stationary phases with traditional phases of similar or like selectivities for applications with a variety of different sample types from a number of industries, including petrochemical, pharmaceutical, environmental, food and beverage, and flavor and fragrance.
At 9:30 am, the session continues with “Application of Fast GC Column Technology to On-line Process Gas Chromatography,” presented by Eric Schmidt, Anna Sandlin, Linda Heinicke, Bill Winniford, Wilco Hoogerwerf, and Jasper Van Noyen, and Dale Ashworth and Chris Bishop of Valco Instruments Company, Inc. The use of fast gas chromatography (GC) column technology as applied to process GC to gather the analytical information needed to better understand, optimize, and probe chemical problems will be discussed.
At 9:50 am, Marijn van Harmelen of Pac AC Analytical Controls will present “CNS SIMDIS-Boiling Point Distribution Data for Carbon, Sulfur and Nitrogen in Crude Oil,” which will examine how adding specific sulfur and nitrogen chemiluminescence detectors (SCD & NCD) to a HT Simulated distillation (SIMDIS) will provide an analyzer that generates complete hydrocarbon, sulfur, and nitrogen boiling point distribution data in less than 30 min, without any sample preparation.
The Chromatography session concludes with the 10:30 am discussion “Polyarc Advancements Reduce the Dependence on Complex Standards for Trace Impurities by GC/FID,” presented by W. Christopher Siegler, Marla Gilbert, James Griffith, Bill Winniford, and Jim Luong of Dow Chemical Company, and Andrew Jones of Activated Research Company. The rapid and accurate quantification of a wide variety of compounds for trace impurity analyses using a commercial post-column reaction system from ARC called the Polyarc Ultra is demonstrated.
Influence of Concentration in Conventional GPC/SEC and Advanced Detection GPC/SEC
March 21st 2025Sample concentration is a parameter that can influence the quality of gel permeation chromatography/size-exclusion chromatography (GPC/SEC) separations and the obtained results. Understanding this influence can help to support the development of reliable GPC/SEC methods.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.