To reach satisfactory results in terms of accurate retention time prediction, new in silico optimization approaches must be considered.
This article will discuss the benefits of 2D-LC and multiple application areas in (bio)pharmaceutical analysis, and will highlight the challenges and future outlook.
An introduction from the guest editors of this special supplement from LCGC Europe focusing on recent trends in pharmaceutical analysis.
This study demonstrates a new LEAN approach and method, where 25 solvents can be simultaneously determined based on predetermined relative response factors (RRFs) against an internal standard (decane) with only one injection of sample solution.