Davy Guillarme | Authors

Articles

Optimizing MS-Compatible Mobile Phases for IEX Separation of Monoclonal Antibodies

The impact of ionic strength, buffer capacity, and pH-response on the retention behavior and peak shape of mAb species characterization is evaluated for IEX-MS. The aim of the present study was to understand the impact of ionic strength, buffer capacity, and pH-response on the retention behavior and peak shape of mAb species.