Erik L. Regalado

To reach satisfactory results in terms of accurate retention time prediction, new in silico optimization approaches must be considered.

Unlike reversed-phase liquid chromatography, SFC lacks a universal stationary phase. Thus, it is important to re-evaluate the default column screening library used with SFC. In this study, three uncommon achiral SFC columns were investigated and compared to three popular stationary phases.

In this study, we describe a simple and rapid liquid chromatography–mass spectrometry (LC–MS) method for the evaluation of caffeine, taurine, and aspartame in teas, soft drinks, and energy drinks using high performance liquid chromatography (HPLC) coupled with electrospray ionization (ESI)-MS detection and multiple injections in a single experimental run (MISER) analysis.

This article describes a simple and rapid LC–MS method for evaluation of caffeine, taurine, and aspartame in teas, soft drinks, and energy drinks using HPLC coupled with electrospray ionization mass spectrometry detection and MISER analysis.