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© 2023 MJH Life Sciences™ and Chromatography Online. All rights reserved.
Corianne E. Randstrom is with AbbVie Inc., Small Molecule Analytical R&D Department of AbbVie Inc., in North Chicago, Illinois.
This study suggests a 2D-LC screening method to evaluate peak purity
and ensure specificity in pharmaceutical analysis, thereby promoting
the safe production of medicines by detecting active pharmaceutical
ingredients (API) and related substances.
Adding an inline mixer between the sample injector and column in a liquid chromatography (LC) system can be an effective way to resolve problems with peak shape caused by the sample diluent.