Michael W. Lesslie

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Michael W. Lesslie is with AbbVie Inc., Small Molecule Analytical R&D Department of AbbVie Inc., in North Chicago, Illinois.

Articles

pharmaceutical glass bottles production line | Image Credit: © Kadmy - stock.adobe.com

A Standardized 2D-LC Screening Platform for Peak Purity Determination in Pharmaceutical Analysis

John T. Lawler;Michael W. Lesslie;Corianne E. Randstrom;Yanqun Zhao;Zachary S. Breitbach

June 1st 2023

This study suggests a 2D-LC screening method to evaluate peak purity and ensure specificity in pharmaceutical analysis, thereby promoting the safe production of medicines by detecting active pharmaceutical ingredients (API) and related substances.

Mixing and Mixers in Liquid Chromatography, Part 3: Solutions for Problems with Sample Diluents

Dwight R. Stoll;Zachary S. Breitbach;Jean Chang;Michael W. Lesslie;Gregory Webster;Corianne E. Randstrom

June 1st 2019

Adding an inline mixer between the sample injector and column in a liquid chromatography (LC) system can be an effective way to resolve problems with peak shape caused by the sample diluent.