Dave Thomas

Biotherapeutic peptides and proteins are often PEGylated (covalently bonded to polyethylene glycol polymers) to improve bioavailability, reduce immunogenicity, and extend circulating half-life (1). Achieving the desired properties for each application depends on optimizing the number and site of polymers attached, chain length, and the degree of chain branching.

Increase throughput of the HPLC method for triazine herbicides by employing ultra high-speed liquid chromatography at elevated temperature on a heat stable Thermo Scientific Hypercarb column.