James Hutchings | Authors

Articles

Benzodiazepine and Z-Drug Quantitation Using an Agilent 6430 LC-MS-MS

A method was developed for the quantitation of benzodiazephines in biological samples using an Agilent 6430 Triple Quadrupole LC/MS system. The method displays excellent accuracy and precision using a weighted-quadratic calibration model.

Validation of a Benzodiazepine and Z-Drug Methods Using an Agilent 6430 LC-MS-MS

Validation studies showed that the LC/MS/MS method provides reliable results for the analysis of benzodiazephines and the z-drugs zolpidem, zopiclone and zaleplon that meet acceptable criteria set for this application.

Cannabinoid Quantitation Using an Agilent 6430 LC-MS-MS

Sufficient resolution and peak shape for the targets can be achieved within an overall run time of 12.5 minutes. Additional validation studies confirmed that this method meets all criteria required for routine analysis of cannabinoids in whole blood.

Validation of a Cannabinoid Quantitation Method Using an Agilent 6430 LC-MS-MS

A method was developed for the quantitation of Cannabinoids using an Agilent 6430 Triple Quadrupole LC/MS system. Validation showed that the LC/MS/MS method provides reliable results for the quantitation of THC, OH-THC, and carboxy-THC.