Validation of a Benzodiazepine and Z-Drug Methods Using an Agilent 6430 LC-MS-MS
Validation studies showed that the LC/MS/MS method provides reliable results for the analysis of benzodiazephines and the z-drugs zolpidem, zopiclone and zaleplon that meet acceptable criteria set for this application.
Identifying and Rectifying the Misuse of Retention Indices in GC
December 10th 2024LCGC International spoke to Phil Marriott and Humberto Bizzo about a recent paper they published identifying the incorrect use of retention indices in gas chromatography and how this problem can be rectified in practice.
Overcoming Common Challenges to Determine Residual Impurities Using IC in APIs with Limited Water
December 10th 2024Organic solvents are generally not compatible with ion chromatography (IC) systems. The approach presented here assists the use of organic solvents for sample preparation and provides a mechanism for the removal of the organic solvents from the chromatographic flow path.
