Jeff Patrick

Articles

Comprehensive Analysis of Human Plasma Using Gas Chromatography–High Resolution Time-of-Flight Mass Spectrometry: A Workflow to Leverage Electron and Chemical Ionization

Jeff Patrick;John Heim;Joe Binkley;David E. Alonso

October 1st 2013

Gas chromatography with electron ionization and mass spectrometry (GC–EI-MS) detection is a workhorse among analytical techniques in metabolomics. A major challenge in the utilization of GC–EI-MS in metabolomics is the identification of unknowns.

Direct Analysis Serum Lipidomics Using High Performance Time of Flight Mass Spectrometry — High Resolution, Accurate Mass, and Zucker Rats

Kevin Siek;Jeff Patrick;Stephanie Amaya;LECO Corporation;Joe Binkley

February 1st 2013

Polar lipids and other metabolites extracted from plasma from lean, diabetic, and obese Zucker rats were analyzed by flow injection using high resolution time of flight mass spectrometry. Metabolites were confidently identified and differences in the metabolite profiles determined.

Characterization of Metabolites in Neat Rice Leaf Extracts Using High Resolution Time of Flight Mass Spectrometry Coupled to Gas Chromatography

Jeff Patrick;LECO Corporation

June 1st 2012

Plant materials contain a wealth of information on plant viability and health. The analysis of the metabolite contents of the leaves of various plants has been informative in the comparison of organisms.