Joe Binkley | Authors

High resolution time-of-flight mass spectrometry (HR-TOF-MS) with a novel multimode ionization source together with enhanced chromatographic resolution can successfully detect and identify pollutants in household dust samples. Here’s how.

In this study, general extract screening of food storage materials was done with nontargeted analytical methods to understand what analytes could potentially leach into food or beverages. GC and mass spectral deconvolution effectively separated analytes within the complex mixture and TOF-MS provided full mass range spectral data for identification. This workflow can be used for confident characterization of components present as extractables from food packaging materials.

Enhanced chromatographic resolution (GC×GC), increased resolving power with high-resolution TOF-MS, and software designed to leverage these attributes are combined to provide data that are easy to process and interpret.

Direct exposure probe (DEP) coupled to the Pegasus HT, time-of-flight mass spectrometer, was used for the identification of synthetic cannabinoids in MTN-series compounds.

Gas chromatography with electron ionization and mass spectrometry (GC–EI-MS) detection is a workhorse among analytical techniques in metabolomics. A major challenge in the utilization of GC–EI-MS in metabolomics is the identification of unknowns.

The application of high-resolution TOF-MS to petroleomics is presented, and the basic theory of each type of ultrahigh-resolution mass spectral platform is briefly explained.