
LECO Corporation
Articles by LECO Corporation


Webinar Date/Time: Wed, Apr 10, 2024 10:00 AM EDT

John Hayes (Separation Science Product Manager, LECO Corporation) showcases LECO's newest technology and explains how they fit into the current market.

Webinar Date/Time: Monday, May 22nd, 2023 Morning Session: 9am EDT | 6am PDT | 2pm BST | 3pm CEST Lunchtime Session: 1pm EDT | 10am PDT | 6pm BST | 7pm CEST Afternoon Session: 2pm EDT | 11am PDT | 7pm BST | 8pm CEST Tuesday, May 23rd, 2023 Morning Session: 9am EDT | 6am PDT | 2pm BST | 3pm CEST Lunchtime Session: 1pm EDT | 10am PDT | 6pm BST | 7pm CEST Afternoon Session: 2pm EDT | 11am PDT | 7pm BST | 8pm CEST

Studying the small has never been a bigger priority. The diversity of the metabolome requires a diversity of analytical tools to understand it, but no matrix is too complex when you’re properly equipped. Discover how GC-TOFMS and GCxGC can complete your instrument suite.


Wednesday, September 22, 2021 at 12pm BST | 1pm CEST | 7am EDT So you thought GC was a mature technique? Join our global GC experts to find out why this is not true!

Monday, July 19, 2021, 02:00 PM EDT Tuesday, July 20, 2021, 02:00 PM EDT Join us for this free online event to learn about important developments in the analysis of contaminants in a wide range of food and environmental matrices using a range of chromatographic, detection, and sample preparation techniques. A few hours of your time will deliver enormous benefits for your work.

GCxGC TOFMS analysis can be overwhelming, but ChromaTOF Tile can quickly compare these data sets to bring statistically significant differences to the forefront.

***Thursday and Friday May 13-14 | May 20-21, 2021*** In the relaxed and unconventional talks in this symposium, highly experienced speakers from industry and academia will impart key learnings from their long experience with chromatography—from heroic failures that have taught them valuable lessons, to moments of inspirational serendipity, and everything in between. CHROMTalks will deliver lifetimes of learning in condensed form, covering topics across implementation, troubleshooting, and method development of analytical techniques. Time spent at CHROMTalks will pay back as soon as you enter your laboratory! ***Available On Demand Until May 21, 2022***

Pesticide residues in food can cause a number of adverse health effects. By using GCxGC-TOFMS, you can determine exactly what residues are in your food.


The low sensory threshold of 2,4,6-tricholoranisole (TCA), a major contributor of wine cork taint, is hard to detect without a sensitive instrument like the Pegasus® BT.

***Live: Two Day Event! Day One: Thursday, Oct. 22, 2020 10am EDT | 12:30pm EDT | 2pm EDT & Day Two: Friday, Oct. 23, 2020 10am EDT | 2pm EDT *** In this two-day online event, speakers will discuss theory and applications of gas chromatography (GC) and high performance liquid chromatography (HPLC). We have a morning and afternoon session each day, plus a lunchtime tutorial session on 2D-GC on Day 1. There will be live Q&A for the morning sessions and the tutorial. Attendance is free..*** On demand available after final airing until Oct. 23, 2021.***


-GC×GC offers dramatic improvements over traditional gas chromatography for the analysis of complex mixtures in numerous applications -The power and utility of GC×GC technology -The need for more advanced and novel stationary phases for gas-chromatographic columns

• Characterizing cannabis • Terpenes analysis using headspace solid-phase microextraction and GC–MS • LC triple-quad and GCxGC-TOFMS for efficient cannabis testing.


This application note demonstrates how LECO’s Pegasus® GC-HRT paired with its unique ChromaTOF-HRT® brand software, gives users the means to confidently identify “known unknowns” and “unknown unknowns” in swimming pool and hot tub water.

Direct exposure probe (DEP) coupled to the Pegasus HT, time-of-flight mass spectrometer, was used for the identification of synthetic cannabinoids in MTN-series compounds.

Polar lipids and other metabolites extracted from plasma from lean, diabetic, and obese Zucker rats were analyzed by flow injection using high resolution time of flight mass spectrometry. Metabolites were confidently identified and differences in the metabolite profiles determined.

Plant materials contain a wealth of information on plant viability and health. The analysis of the metabolite contents of the leaves of various plants has been informative in the comparison of organisms.

Synthetic cannabis products have garnered a great deal of media attention recently. Countless products are being sold at smoke shops, convenience stores, and online sites.

Comprehensive multidimensional gas chromatography time-of-flight mass spectrometry has emerged as an excellent instrumental option for the characterization of small metabolite profiles.

Illegal drug use worldwide is at an all time high. Forensic laboratories are seeing increased sample loads creating an immediate need for fast and accurate analysis to positively identify confiscated materials in criminal investigations. This application highlights the value of gas chromatography with time-of-flight mass spectrometry (GC-TOFMS) for drug testing in forensic laboratories. A method was developed to successfully identify twenty drugs of abuse in 4.5 min. This GC-TOFMS method shows good chromatographic peak shape for even the most challenging drug analytes; even the peak shapes for amphetamine and methamphetamine were exceptional considering they were analyzed underivatized. The total ion chromatogram (TIC) for the twenty drug analytes is shown in Figure 1.
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