To fully characterize a protein biopharmaceutical, it must be broken down into smaller segments (peptides). Several high performance liquid chromatography (HPLC) techniques can be used to provide a wealth of information on everything from post-translational modifications (PTMs) to the glycoprofile to information on similarity when characterizing biosimilars.
Glycosylation is the most common monoclonal antibody (mAb) post‑translational modification. What is essential to know about it?
An excerpt from LCGC’s professional development platform, CHROMacademy.com
An excerpt from LCGC’s professional development platform, CHROMacademy.com
An excerpt from LCGC’s professional development platform, CHROMacademy.com
An excerpt from LCGC’s professional development platform, CHROMacademy.com, on the importance of tuning and calibration in liquid chromatography–mass spectrometry (LC–MS).