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Oliver J. Schmitz | Authors
Articles
Supercritical Fluid Chromatography Coupled with Drift Time Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry as a Tool for Lipid Characterization of HepG2 Cells
Lipids in SFC are mainly separated according to their lipid classes, which simplifies quantification with standards. In this study, SFC coupled with drift time IM‑QTOF-MS was used to characterize the HepG2 lipidome.
Metabolome Studies of Herbal Medicine Using High Performance Liquid Chromatography Ion-Mobility Mass Spectrometry
In Chinese herbal medicine (CHM), traditionally, Hedyotis diffusa and Scutellaria barbata are cooked together and given to patients as tea. It is hypothesized that the interaction of metabolites from both herbs during cooking, improves the medical effect. This hypothesis was tested by preparing two tea variants which were then analyzed using high performance liquid chromatography (HPLC) coupled to ion-mobility mass spectrometry (IM-MS).
Spectral Quality and Reproducibility in Thermal Modulation Comprehensive GCxGC-MS Mass Spectrometer Using a Rapid Scanning Quadrupole
Invented by J. Phillips in 1989, comprehensive GCXGC has strong chromatographic resolving power; from its original petrochemical applications it has been extended to many others. However, coelutions with matrix peaks are often observed and a higher separation power is required.