Spectral Quality and Reproducibility in Thermal Modulation Comprehensive GCxGC-MS Mass Spectrometer Using a Rapid Scanning Quadrupole
The Column
Invented by J. Phillips in 1989, comprehensive GCXGC has strong chromatographic resolving power; from its original petrochemical applications it has been extended to many others. However, coelutions with matrix peaks are often observed and a higher separation power is required.
Invented by J. Phillips in 1989, comprehensive GC×GC has strongchromatographic resolving power; from its original petrochemicalapplications it has been extended to many others. However, coelutionswith matrix peaks are often observed and a higher separation power isrequired. The coupling of GC×GC to mass spectrometry (MS) providesan additional dimension for the identification of compounds concealedunder contour plot displays used in GC×GC.
Inside the Laboratory: The Nontargeted Separations Laboratory at the College of William & Mary
March 25th 2024In this edition of “Inside the Laboratory,” Katelynn Perrault Uptmor, PhD, an assistant professor of chemistry at the College of William and Mary, discusses her group’s current research endeavors, including using complex comparative data obtained from chemical analysis to understand and solve challenges in forensic science and other life science applications.
Using Multidimensional GC Coupled to TOF-MS For the Detection of Tuberculosis-Associated Compounds
March 22nd 2024This study explores the feasibility of using human skin volatile organic compounds (VOCs) analyzed through comprehensive gas chromatography–time of flight–mass spectrometry (GCxGC-TOF-MS) and chemometric techniques, to potentially serve as biomarkers for tuberculosis diagnosis.
Untargeted Analysis in Petroleomics
December 1st 2023LCGC spoke to Leandro Wang Hantao from the University of Campinas in São Paulo, Brazil, about his work investigating the influence of ion management parameters on the data produced by comprehensive gas chromatography–high-resolution mass spectrometry (GC×GC–HRMS) equipped with a fourier transform-orbital ion trap mass analyzer, and his investigation into employing channel occlusion for sample preparation in untargeted analysis in petroleomics.
Gulf Coast Conference: Understanding the Changing Landscape for Clean Energy
October 17th 2023Scott Fenwick, technical director of Clean Fuels Alliance America, was the keynote speaker at the Gulf Coast Conference in Galveston, Texas, where he held a lecture on the growth of biomass-based fuels.
